Sometimes just watching hurts—and the signs of pain are seen in the brain
Patients suffering from CRPS may feel pain and show abnormal brain activations while watching a hand actions. Credit: Jaakko Hotta, Aalto University.
Some people claim to experience pain just watching something painful to happen. This is true especially of people suffering from complex regional pain syndrome (CRPS), a disabling chronic pain disorder in a limb. In CPRS patients, both own movements and just observing other persons’ movements may aggravate the pain.
When you hurt yourself, pain receptors in the body send signals to different parts of the brain. As the result, you experience pain. Researchers in Aalto University, Finland, found that when CRPS patients feel pain caused by observing other person’s movements, their brains display abnormal activation in many such areas that respond to normal physical pain. Thus the pain that the CRPS patients felt during movement observation presented similarities to the “normal” pain associated with tissue damage.
- CPRS is a very complex disease with devastating chronic pain. Its pathophysiology is incompletely understood and definitive biomarkers are lacking. Our discovery may help to develop diagnostics and therapeutic strategies for CRPS patients, tells neurologist Jaakko Hotta, Doctoral Candidate at Aalto University.
In the study, the researchers analyzed functional magnetic resonance images from 13 upper-limb CRPS patients and 13 healthy control subjects who were viewing brief videos of hand actions, such as a hand squeezing a ball with maximum force.
In the CPRS patients, watching hand actions was associated with abnormal brain activation patterns and a pattern-classification analysis differentiated the patients from the healthy subjects. These findings indicate that CRPS affects brain areas related to both pain processing and motor control.
The study was published on the Journal of Pain, the official journal of the American Pain Society.
For more information:
Jaakko Hotta, Doctoral Candidate / Neurologist
Aalto University, School of Science
jaakko.hotta@aalto.fi
Tel: +358 50 57 12640
Research article: Jaakko Hotta, Jukka Saari, Miika Koskinen, Yevhen Hlushchuk, Nina Forss, Riitta Hari: Abnormal brain responses to action observation in complex regional pain syndrome. Journal of Pain 2016.
Read more news
Time crystals could power future quantum computers
A time crystal, a long-life quantum system approaching perpetual motion, has been hooked up to its environment for the first time, unlocking an intriguing way to increase quantum computational and sensing power.
Glitch artwork challenges to see art in a different light
Laura Könönen's sculpture was unveiled on 14 October at the Otaniemi campus.
Nanoparticles in Functional Textiles
Dr. Md. Reazuddin Repon, Postdoctoral Researcher at the Textile Chemistry Group, Department of Bioproducts and Biosystems, Aalto University, has contributed as an editor to a newly published academic volume titled “Nanoparticles Integrated Functional Textiles”.